| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes |
| 1916 | 11/3 | George Wythe | 18 | 0 | W | 1 | Away | Wytheville | ||||||
| 1918 | 11/14 | George Wythe | 106 | 0 | W | 1 | Home | Radford | ||||||
| 1918 | George Wythe | 38 | 0 | W | 1 | Home | Radford | |||||||
| 1919 | 11/4 | George Wythe | 53 | 0 | W | 1 | Home | Radford | ||||||
| 1929 | George Wythe | 0 | 0 | T | 1 | Emmett Weddle | ||||||||
| 1930 | 10/3 | George Wythe | 12 | 0 | W | 1 | Away | Wytheville | Eversham Stadium | Arthur Giesen | ||||
| 1931 | 11/11 | George Wythe | 19 | 0 | W | 1 | Home | Radford | Arthur Giesen | |||||
| 1933 | 11/11 | George Wythe | 0 | 7 | L | 1 | Away | Wytheville | Evansham Stadium | Arthur Giesen | ||||
| 1939 | 9/29 | George Wythe | 6 | 6 | T | 1 | Home | Radford | Arthur Giesen | |||||
| 1940 | 9/27 | George Wythe | 0 | 7 | L | 1 | Away | Wytheville | Eversham Stadium | Harold Weekley | ||||
| 1941 | 9/26 | George Wythe | 7 | 18 | L | 1 | Home | Radford | Radford High Stadium | Marion Roberts | ||||
| 1943 | 9/17 | George Wythe | 13 | 0 | W | 1 | Away | Wytheville | Eversham Stadium | Fred McCoy | ||||
| 1943 | 11/5 | George Wythe | 25 | 0 | W | 1 | Home | Radford | Fred McCoy | |||||
| 1944 | 10/13 | George Wythe | 0 | 0 | T | 1 | Away | Wytheville | Eversham Stadium | Fred McCoy | ||||
| 1945 | 10/19 | George Wythe | 28 | 6 | W | 1 | Home | Radford | Happy Hobgood | |||||
| 1946 | 10/19 | George Wythe | 18 | 0 | W | 1 | Away | Wytheville | Eversham Stadium | Fred McCoy | ||||
| 1947 | 10/17 | George Wythe | 0 | 12 | L | 1 | Home | Radford | Radford High Stadium | Fred McCoy | ||||
| 1948 | 10/15 | George Wythe | 0 | 6 | L | 1 | Away | Wytheville | Eversham Stadium | Fred McCoy | ||||
| 1949 | 10/14 | George Wythe | 7 | 13 | L | 1 | Home | Radford | Radford High Stadium | Fred McCoy | ||||
| 1951 | 10/19 | George Wythe | 0 | 46 | L | 1 | Away | Wytheville | Withers Field | Fred McCoy | ||||
| 1952 | 10/17 | George Wythe | 0 | 7 | L | 1 | Home | Radford | Radford High Stadium | Fred McCoy | ||||
| 1953 | 10/16 | George Wythe | 0 | 20 | L | 1 | Away | Wytheville | Withers Field | Jimmy Painter | ||||
| 1954 | 10/16 | George Wythe | 20 | 6 | W | 1 | Home | Radford | Radford High Stadium | Jimmy Painter | ||||
| 1958 | 10/17 | George Wythe | 12 | 6 | W | 1 | Away | Wytheville | Withers Field | Jimmy Painter | ||||
| 1959 | 10/16 | George Wythe | 43 | 12 | W | 1 | Home | Radford | Radford High Stadium | Bob Williams | ||||
| 1960 | 9/9 | George Wythe | 33 | 0 | W | 1 | Away | Wytheville | Withers Field | Bob Williams | ||||
| 1961 | 9/8 | George Wythe | 12 | 0 | W | 1 | Home | Radford | Radford High Stadium | Bob Williams | ||||
| 1962 | 9/14 | George Wythe | 7 | 22 | L | 1 | Away | Wytheville | Withers Field | Robby Roberson | ||||
| 1963 | 9/13 | George Wythe | 20 | 6 | W | 1 | Home | Radford | Radford High Stadium | Tammy Farnsworth | ||||
| 1964 | 9/11 | George Wythe | 14 | 14 | T | 1 | Away | Wytheville | Withers Field | Tammy Farnsworth | ||||
| 1965 | 9/10 | George Wythe | 6 | 13 | L | 1 | Home | Radford | Radford High Stadium | Tammy Farnsworth | ||||
| 1966 | 11/4 | George Wythe | 7 | 31 | L | 1 | Away | Wytheville | Withers Field | Tammy Farnsworth | ||||
| 1967 | 11/3 | George Wythe | 15 | 9 | W | 1 | Home | Radford | Radford High Stadium | Harold Absher | ||||
| 1968 | 10/18 | George Wythe | 12 | 9 | W | 1 | Away | Wytheville | Withers Field | Harold Absher | ||||
| 1969 | 10/17 | George Wythe | 34 | 16 | W | 1 | Home | Radford | Radford High Stadium | Harold Absher | ||||
| 1970 | 10/30 | George Wythe | 8 | 0 | W | 1 | Away | Wytheville | Withers Field | Norman Lineburg | ||||
| 1971 | 10/29 | George Wythe | 22 | 13 | W | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 1972 | 10/27 | George Wythe | 38 | 0 | W | 1 | Away | Wytheville | Withers Field | Norman Lineburg | ||||
| 1973 | 10/26 | George Wythe | 26 | 27 | L | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 1974 | 10/25 | George Wythe | 35 | 12 | W | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 1975 | 10/24 | George Wythe | 16 | 12 | W | 1 | Away | Wytheville | Withers Field | Norman Lineburg | ||||
| 1976 | 10/22 | George Wythe | 33 | 23 | W | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 1977 | 10/21 | George Wythe | 55 | 14 | W | 1 | Away | Wytheville | Withers Field | Norman Lineburg | ||||
| 1978 | 10/20 | George Wythe | 21 | 20 | W | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 1979 | 10/26 | George Wythe | 6 | 17 | L | 1 | Away | Wytheville | Pendleton Field | Norman Lineburg | ||||
| 1980 | 10/24 | George Wythe | 15 | 12 | W | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 1981 | 10/23 | George Wythe | 13 | 33 | L | 1 | Away | Wytheville | Pendleton Field | Norman Lineburg | ||||
| 1982 | 10/22 | George Wythe | 45 | 12 | W | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 1983 | 10/21 | George Wythe | 2 | 7 | L | 1 | Away | Wytheville | Pendleton Field | Norman Lineburg | ||||
| 1984 | 10/26 | George Wythe | 17 | 0 | W | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 1985 | 10/25 | George Wythe | 20 | 3 | W | 1 | Away | Wytheville | Pendleton Field | Norman Lineburg | ||||
| 1986 | 10/24 | George Wythe | 22 | 8 | W | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 1987 | 10/23 | George Wythe | 29 | 0 | W | 1 | Away | Wytheville | Pendleton Field | Norman Lineburg | ||||
| 1988 | 10/21 | George Wythe | 29 | 0 | W | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 1989 | 10/20 | George Wythe | 41 | 12 | W | 1 | Away | Wytheville | Pendleton Field | Norman Lineburg | ||||
| 1999 | 9/3 | George Wythe | 13 | 14 | L | 1 | Away | Wytheville | Pendleton Field | Norman Lineburg | ||||
| 2000 | 8/31 | George Wythe | 3 | 12 | L | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 2000 | 11/10 | George Wythe | 3 | 0 | W | 1 | Away | Wytheville | Pendleton Field | Norman Lineburg | playoff at Wytheville | |||
| 2001 | 9/7 | George Wythe | 14 | 7 | W | 1 | Away | Wytheville | Pendleton Field | Norman Lineburg | ||||
| 2002 | 9/6 | George Wythe | 26 | 21 | W | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 2002 | 11/15 | George Wythe | 7 | 33 | L | 1 | Away | Wytheville | Pendleton Field | Norman Lineburg | playoff at Wytheville | |||
| 2003 | 9/5 | George Wythe | 24 | 14 | W | 1 | Away | Wytheville | Pendleton Field | Norman Lineburg | ||||
| 2003 | 11/21 | George Wythe | 23 | 22 | W | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | playoff at Radford | |||
| 2004 | 9/10 | George Wythe | 0 | 33 | L | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 2005 | 9/9 | George Wythe | 7 | 19 | L | 1 | Away | Wytheville | Pendleton Field | Norman Lineburg | ||||
| 2006 | 9/8 | George Wythe | 14 | 13 | W | 1 | Home | Radford | Radford High Stadium | Norman Lineburg | ||||
| 2007 | 9/7 | George Wythe | 16 | 19 | L | 1 | Away | Wytheville | Pendleton Field | Matthew Saunders | ||||
| 2008 | 9/5 | George Wythe | 20 | 13 | W | 1 | Home | Radford | Radford High Stadium | Matthew Saunders | ||||
| 2009 | 9/11 | George Wythe | 19 | 21 | L | 1 | Away | Wytheville | Pendleton Field | Matthew Saunders | ||||
| 2009 | 11/20 | George Wythe | 33 | 28 | W | 1 | Away | Wytheville | Pendleton Field | Matthew Saunders | playoff at Wytheville | |||
| 2010 | 9/10 | George Wythe | 36 | 35 | W | 1 | Home | Radford | Radford High Stadium | Matthew Saunders | ||||
| 2010 | 11/19 | George Wythe | 26 | 0 | W | 1 | Home | Radford | Radford High Stadium | Matthew Saunders | playoff at Radford | |||
| 2011 | 9/9 | George Wythe | 7 | 10 | L | 1 | Away | Wytheville | Pendleton Field | Matthew Saunders | ||||
| 2011 | 11/18 | George Wythe | 10 | 22 | L | 1 | Away | Wytheville | Pendleton Field | Matthew Saunders | playoff at Wytheville | |||
| 2012 | 9/7 | George Wythe | 31 | 44 | L | 1 | Home | Radford | Radford High Stadium | Matthew Saunders | ||||
| 2013 | 8/30 | George Wythe | 14 | 21 | L | 1 | Away | Wytheville | Pendleton Field | Matthew Saunders | ||||
| 2014 | 8/29 | George Wythe | 35 | 14 | W | 1 | Home | Radford | Radford High Stadium | Matthew Saunders | ||||
| 2015 | 8/28 | George Wythe | 55 | 27 | W | 1 | Away | Wytheville | Pendleton Field | Matthew Saunders | ||||
| 2015 | 11/28 | George Wythe | 28 | 35 | L | 1 | Away | Wytheville | Pendleton Field | Matthew Saunders | playoff at Wytheville | |||
| 2016 | 8/26 | George Wythe | 0 | 56 | L | 1 | Home | Radford | Radford High Stadium | Matthew Saunders | ||||
| 2017 | 8/25 | George Wythe | 18 | 26 | L | 1 | Home | Radford | Radford High Stadium | Matthew Saunders | ||||
| 2018 | 8/24 | George Wythe | 34 | 13 | W | 1 | Away | Wytheville | Pendleton Field | Matthew Saunders | ||||
| 2019 | 8/30 | George Wythe | 45 | 23 | W | 1 | Home | Radford | Radford High Stadium | Matthew Saunders | ||||
| 2021 | 8/27 | George Wythe | 35 | 6 | W | 1 | Home | Radford | Radford High Stadium | Michael Crist | ||||
| 2022 | 8/25 | George Wythe | 29 | 15 | W | 1 | Away | Wytheville | Pendleton Field | Michael Crist | ||||
| 2023 | 8/25 | George Wythe | 42 | 7 | W | 1 | Home | Radford | Radford High Stadium | Michael Crist | ||||
| 2024 | 8/30 | George Wythe | 7 | 28 | L | 1 | Away | Wytheville | Pendleton Field | Michael Crist | ||||
| 2025 | 8/29 | George Wythe | 31 | 20 | W | 1 | Home | Radford | Radford High Stadium | Michael Crist | ||||
| 2026 | 8/28 | George Wythe | 40 | 0 | W | 1 | Away | Wytheville | Pendleton Field | Michael Crist | ||||
| 1,823 | 1,188 | 54 | 31 | 4 | .629 | |||||||||
| 20.48 | 13.35 | 7.13 |