| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes |
| 1920 | 9/24 | George Wythe | 67 | 0 | W | 1 | Home | Blacksburg | ||||||
| 1935 | 11/1 | George Wythe | 0 | 7 | L | 1 | Away | Wytheville | ||||||
| 1936 | 10/2 | George Wythe | 6 | 14 | L | 1 | Home | Blacksburg | Dick Davenport | |||||
| 1937 | 10/1 | George Wythe | 0 | 34 | L | 1 | Away | Wytheville | Eversham Stadium | Dick Davenport | ||||
| 1938 | 10/29 | George Wythe | 7 | 12 | L | 1 | Home | Blacksburg | Dick Davenport | |||||
| 1939 | 10/6 | George Wythe | 16 | 13 | W | 1 | Away | Wytheville | Eversham Stadium | W. H. Devlin | ||||
| 1940 | 10/4 | George Wythe | 6 | 26 | L | 1 | Away | Wytheville | Eversham Stadium | W. H. Devlin | ||||
| 1941 | 10/3 | George Wythe | 6 | 0 | W | 1 | Away | Wytheville | Eversham Stadium | Joe Newman | ||||
| 1942 | 10/2 | George Wythe | 13 | 6 | W | 1 | Away | Wytheville | Eversham Stadium | Joe Newman | ||||
| 1945 | 9/21 | George Wythe | 0 | 33 | L | 1 | Home | Blacksburg | George Hawkins | |||||
| 1946 | 10/4 | George Wythe | 0 | 0 | T | 1 | Away | Wytheville | Eversham Stadium | Michael Spann | ||||
| 1947 | 10/3 | George Wythe | 6 | 27 | L | 1 | Home | Blacksburg | Miles Stadium | Michael Spann | ||||
| 1960 | 10/14 | George Wythe | 6 | 13 | L | 1 | Away | Wytheville | Withers Field | Ken Stickley | ||||
| 1961 | 10/13 | George Wythe | 60 | 0 | W | 1 | Home | Blacksburg | Bill Brown Stadium | Ken Stickley | ||||
| 1962 | 10/19 | George Wythe | 26 | 7 | W | 1 | Away | Wytheville | Withers Field | Ken Stickley | ||||
| 1963 | 10/18 | George Wythe | 32 | 13 | W | 1 | Home | Blacksburg | Bill Brown Stadium | Ken Stickley | ||||
| 1968 | 11/1 | George Wythe | 6 | 23 | L | 1 | Away | Wytheville | Withers Field | Cam Wiley | ||||
| 1969 | 10/31 | George Wythe | 16 | 8 | W | 1 | Home | Blacksburg | Bill Brown Stadium | John David | ||||
| 1970 | 11/6 | George Wythe | 6 | 6 | T | 1 | Away | Wytheville | Withers Field | John David | ||||
| 1971 | 11/5 | George Wythe | 14 | 14 | T | 1 | Home | Blacksburg | Bill Brown Stadium | John David | ||||
| 1972 | 11/3 | George Wythe | 6 | 32 | L | 1 | Away | Wytheville | Withers Field | John David | ||||
| 1973 | 11/2 | George Wythe | 45 | 24 | W | 1 | Home | Blacksburg | Bill Brown Stadium | Vestor Newcomb | ||||
| 1974 | 10/18 | George Wythe | 21 | 6 | W | 1 | Away | Wytheville | Withers Field | Vestor Newcomb | ||||
| 1975 | 10/18 | George Wythe | 31 | 0 | W | 1 | Home | Blacksburg | Bill Brown Stadium | Dave Crist | ||||
| 1976 | 10/15 | George Wythe | 43 | 0 | W | 1 | Away | Wytheville | Withers Field | Dave Crist | ||||
| 1977 | 10/14 | George Wythe | 33 | 22 | W | 1 | Home | Blacksburg | Bill Brown Stadium | Dave Crist | ||||
| 1978 | 10/13 | George Wythe | 6 | 0 | W | 1 | Away | Wytheville | Pendleton Field | Dave Crist | ||||
| 1979 | 10/19 | George Wythe | 3 | 0 | W | 1 | Home | Blacksburg | Bill Brown Stadium | Dave Crist | ||||
| 1980 | 10/17 | George Wythe | 20 | 0 | W | 1 | Away | Wytheville | Pendleton Field | Dave Crist | ||||
| 1981 | 10/16 | George Wythe | 21 | 0 | W | 1 | Home | Blacksburg | Bill Brown Stadium | Dave Crist | ||||
| 1982 | 10/15 | George Wythe | 7 | 13 | L | 1 | Away | Wytheville | Pendleton Field | Dave Crist | ||||
| 1983 | 10/14 | George Wythe | 0 | 6 | L | 1 | Home | Blacksburg | Bill Brown Stadium | Dave Crist | ||||
| 1984 | 10/19 | George Wythe | 14 | 8 | W | 1 | Away | Wytheville | Pendleton Field | Dave Crist | ||||
| 1985 | 10/18 | George Wythe | 21 | 3 | W | 1 | Home | Blacksburg | Bill Brown Stadium | Dave Crist | ||||
| 1986 | 10/17 | George Wythe | 39 | 8 | W | 1 | Away | Wytheville | Pendleton Field | Dave Crist | ||||
| 1987 | 10/16 | George Wythe | 12 | 0 | W | 1 | Home | Blacksburg | Bill Brown Stadium | Dave Crist | ||||
| 1988 | 10/14 | George Wythe | 42 | 6 | W | 1 | Away | Wytheville | Pendleton Field | Dave Crist | ||||
| 1989 | 10/13 | George Wythe | 19 | 0 | W | 1 | Home | Blacksburg | Bill Brown Stadium | Dave Crist | ||||
| 676 | 384 | 23 | 12 | 3 | .645 | |||||||||
| 17.79 | 10.11 | 7.68 | ||||||||||||