| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Place | Location | Field | Coach | Notes |
| 1950 | 11/23 | St. Xavier Louisville | 13 | 20 | L | 1 | Neutral | Lexington | Stoll Field | Ewell Waddell | Shrine Bowl | |||
| 1972 | 9/8 | St. Xavier Louisville | 10 | 7 | W | 1 | Home | Fort Thomas | David Cecil Memorial Stadium | Mike Murphy | ||||
| 1973 | 9/8 | St. Xavier Louisville | 6 | 41 | L | 1 | Away | Louisville | Manual Stadium | Mike Murphy | ||||
| 1996 | 8/31 | St. Xavier Louisville | 22 | 17 | W | 1 | Neutral | Lexington | Roy G. Walton Stadium | Dale Mueller | Thoroughbred Bowl | |||
| 2005 | 9/9 | St. Xavier Louisville | 0 | 45 | L | 1 | Away | Louisville | Dale Mueller | |||||
| 2006 | 9/9 | St. Xavier Louisville | 21 | 35 | L | 1 | Neutral | Cincinnati | Paul Brown Stadium | Dale Mueller | ||||
| 2015 | 9/18 | St. Xavier Louisville | 6 | 37 | L | 1 | Home | Fort Thomas | David Cecil Memorial Stadium | Brian Weinrich | ||||
| 2016 | 9/16 | St. Xavier Louisville | 18 | 45 | L | 1 | Away | Louisville | Brian Weinrich | |||||
| 96 | 247 | 2 | 6 | 0 | .250 | |||||||||
| 12.00 | 30.88 | -18.88 | ||||||||||||