| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes |
| 1925 | 9/25 | Science Hill | 0 | 46 | L | 1 | Away | Johnson City | Keystone Field | Albert Choate | ||||
| 1926 | 10/22 | Science Hill | 0 | 7 | L | 1 | Away | Johnson City | Keystone Field | Mule Brown | ||||
| 1927 | 11/4 | Science Hill | 7 | 25 | L | 1 | Away | Johnson City | Keystone Field | Mule Brown | ||||
| 1928 | 11/12 | Science Hill | 6 | 6 | T | 1 | Away | Johnson City | Keystone Field | Mule Brown | ||||
| 1929 | 11/8 | Science Hill | 8 | 6 | W | 1 | Away | Johnson City | Keystone Field | Mule Brown | ||||
| 1930 | 11/7 | Science Hill | 7 | 6 | W | 1 | Home | Elizabethton | Bemberg-Glanstoff Field | Mule Brown | ||||
| 1931 | 11/6 | Science Hill | 7 | 0 | W | 1 | Away | Johnson City | Keystone Field | Mule Brown | ||||
| 1932 | 11/4 | Science Hill | 0 | 0 | T | 1 | Home | Elizabethton | Bemberg-Glanstoff Field | Mule Brown | ||||
| 1933 | 11/3 | Science Hill | 0 | 33 | L | 1 | Away | Johnson City | Keystone Field | Mule Brown | ||||
| 1934 | 11/9 | Science Hill | 0 | 46 | L | 1 | Home | Elizabethton | Cherokee Field | Mule Brown | ||||
| 1935 | 11/8 | Science Hill | 0 | 19 | L | 1 | Away | Johnson City | Roosevelt Stadium | Mule Brown | ||||
| 1936 | 11/6 | Science Hill | 7 | 0 | W | 1 | Home | Elizabethton | Cherokee Field | Mule Brown | ||||
| 1937 | 11/5 | Science Hill | 18 | 0 | W | 1 | Away | Johnson City | Roosevelt Stadium | Mule Brown | ||||
| 1938 | 11/4 | Science Hill | 46 | 0 | W | 1 | Home | Elizabethton | Cherokee Field | Mule Brown | ||||
| 1939 | 11/3 | Science Hill | 0 | 7 | L | 1 | Away | Johnson City | Roosevelt Stadium | Mule Brown | ||||
| 1940 | 10/30 | Science Hill | 0 | 31 | L | 1 | Home | Elizabethton | Cherokee Field | Mule Brown | ||||
| 1941 | 10/29 | Science Hill | 13 | 6 | W | 1 | Away | Johnson City | Roosevelt Stadium | Mule Brown | ||||
| 1942 | 10/28 | Science Hill | 19 | 6 | W | 1 | Home | Elizabethton | Mule Brown | |||||
| 1943 | 10/29 | Science Hill | 67 | 7 | W | 1 | Away | Johnson City | Roosevelt Stadium | Mule Brown | ||||
| 1944 | 10/27 | Science Hill | 20 | 6 | W | 1 | Home | Elizabethton | Mule Brown | |||||
| 1945 | 11/23 | Science Hill | 46 | 6 | W | 1 | Away | Johnson City | Roosevelt Stadium | Mule Brown | ||||
| 1946 | 10/25 | Science Hill | 7 | 0 | W | 1 | Home | Elizabethton | Mule Brown | |||||
| 1947 | 10/24 | Science Hill | 13 | 6 | W | 1 | Away | Johnson City | Memorial Stadium | Mule Brown | ||||
| 1948 | 10/22 | Science Hill | 21 | 26 | L | 1 | Home | Elizabethton | Childress Stadium | Dwight Haynes | ||||
| 1949 | 10/21 | Science Hill | 0 | 7 | L | 1 | Away | Johnson City | Memorial Stadium | Dwight Haynes | ||||
| 1950 | 10/20 | Science Hill | 6 | 27 | L | 1 | Home | Elizabethton | Childress Stadium | John Treadway | ||||
| 1951 | 10/19 | Science Hill | 19 | 7 | W | 1 | Away | Johnson City | Memorial Stadium | John Treadway | ||||
| 1952 | 10/17 | Science Hill | 0 | 0 | T | 1 | Home | Elizabethton | Childress Stadium | John Treadway | ||||
| 1953 | 10/16 | Science Hill | 39 | 13 | W | 1 | Away | Johnson City | Memorial Stadium | John Treadway | ||||
| 1954 | 10/22 | Science Hill | 38 | 7 | W | 1 | Home | Elizabethton | Childress Stadium | John Treadway | ||||
| 1955 | 10/21 | Science Hill | 19 | 19 | T | 1 | Away | Johnson City | Memorial Stadium | John Treadway | ||||
| 1956 | 10/19 | Science Hill | 20 | 32 | L | 1 | Home | Elizabethton | Childress Stadium | John Treadway | ||||
| 1957 | 10/18 | Science Hill | 7 | 19 | L | 1 | Away | Johnson City | Memorial Stadium | Claude Holsclaw | ||||
| 1958 | 10/17 | Science Hill | 14 | 44 | L | 1 | Home | Elizabethton | Childress Stadium | Claude Holsclaw | ||||
| 1959 | 10/16 | Science Hill | 0 | 14 | L | 1 | Away | Johnson City | Memorial Stadium | Tom Pugh | ||||
| 1960 | 10/14 | Science Hill | 0 | 7 | L | 1 | Home | Elizabethton | Childress Stadium | Tom Pugh | ||||
| 1961 | 10/13 | Science Hill | 6 | 13 | L | 1 | Away | Johnson City | Memorial Stadium | Tom Pugh | ||||
| 1962 | 10/12 | Science Hill | 6 | 14 | L | 1 | Home | Elizabethton | Childress Stadium | Ernest Cosson | ||||
| 1963 | 10/11 | Science Hill | 7 | 7 | T | 1 | Away | Johnson City | Memorial Stadium | Ernest Cosson | ||||
| 1964 | 10/17 | Science Hill | 0 | 20 | L | 1 | Home | Elizabethton | Childress Stadium | Ernest Cosson | ||||
| 1965 | 10/15 | Science Hill | 0 | 6 | L | 1 | Away | Johnson City | Memorial Stadium | Lynn Goddard | ||||
| 1966 | 10/14 | Science Hill | 14 | 34 | L | 1 | Home | Elizabethton | Childress Stadium | Lynn Goddard | ||||
| 1967 | 10/13 | Science Hill | 13 | 39 | L | 1 | Away | Johnson City | Memorial Stadium | Lynn Goddard | ||||
| 1968 | 10/18 | Science Hill | 0 | 14 | L | 1 | Home | Elizabethton | Childress Stadium | Lynn Goddard | ||||
| 1969 | 10/17 | Science Hill | 26 | 14 | W | 1 | Away | Johnson City | Memorial Stadium | Lynn Goddard | ||||
| 1970 | 10/16 | Science Hill | 6 | 19 | L | 1 | Home | Elizabethton | Childress Stadium | Lynn Goddard | ||||
| 1971 | 10/15 | Science Hill | 35 | 22 | W | 1 | Away | Johnson City | Memorial Stadium | Lynn Goddard | ||||
| 1972 | 10/13 | Science Hill | 30 | 8 | W | 1 | Home | Elizabethton | Childress Stadium | Lynn Goddard | ||||
| 1973 | 10/19 | Science Hill | 7 | 6 | W | 1 | Away | Johnson City | Memorial Stadium | Lynn Goddard | ||||
| 1974 | 10/18 | Science Hill | 7 | 35 | L | 1 | Home | Elizabethton | Childress Stadium | Larry Alderson | ||||
| 1975 | 10/17 | Science Hill | 19 | 36 | L | 1 | Away | Johnson City | Memorial Stadium | Larry Alderson | ||||
| 1976 | 10/15 | Science Hill | 14 | 15 | L | 1 | Home | Elizabethton | Brown Childress Stadium | Dave Rider | ||||
| 1977 | 9/30 | Science Hill | 14 | 25 | L | 1 | Away | Johnson City | Memorial Stadium | Dave Rider | ||||
| 1978 | 9/29 | Science Hill | 21 | 2 | W | 1 | Home | Elizabethton | Brown Childress Stadium | Dave Rider | ||||
| 1979 | 10/12 | Science Hill | 0 | 7 | L | 1 | Away | Johnson City | Memorial Stadium | Dave Rider | ||||
| 1980 | 10/10 | Science Hill | 26 | 18 | W | 1 | Home | Elizabethton | Brown Childress Stadium | Dave Rider | ||||
| 1981 | 10/9 | Science Hill | 8 | 14 | L | 1 | Away | Johnson City | Memorial Stadium | Dave Rider | ||||
| 1982 | 10/8 | Science Hill | 7 | 0 | W | 1 | Home | Elizabethton | Brown Childress Stadium | Dave Rider | ||||
| 1983 | 10/7 | Science Hill | 10 | 13 | L | 1 | Away | Johnson City | Memorial Stadium | Dave Rider | ||||
| 1984 | 10/12 | Science Hill | 15 | 28 | L | 1 | Home | Elizabethton | Brown Childress Stadium | Dave Rider | ||||
| 1985 | 10/11 | Science Hill | 15 | 36 | L | 1 | Away | Johnson City | Memorial Stadium | Dave Rider | ||||
| 1986 | 10/10 | Science Hill | 3 | 7 | L | 1 | Home | Elizabethton | Brown Childress Stadium | Dave Rider | ||||
| 1987 | 9/25 | Science Hill | 0 | 18 | L | 1 | Away | Johnson City | Memorial Stadium | Dave Rider | ||||
| 1988 | 9/23 | Science Hill | 20 | 14 | W | 1 | Home | Elizabethton | Brown Childress Stadium | Dave Rider | ||||
| 1989 | 9/15 | Science Hill | 0 | 7 | L | 1 | Away | Johnson City | Memorial Stadium | Jim Perkins | ||||
| 1990 | 9/14 | Science Hill | 14 | 6 | W | 1 | Home | Elizabethton | Brown Childress Stadium | Dave Rider | ||||
| 1991 | 9/20 | Science Hill | 7 | 17 | L | 1 | Away | Johnson City | Memorial Stadium | Dave Rider | ||||
| 1992 | 9/18 | Science Hill | 21 | 14 | W | 1 | Home | Elizabethton | Brown Childress Stadium | Dave Rider | ||||
| 1993 | 9/3 | Science Hill | 13 | 6 | W | 1 | Away | Johnson City | Memorial Stadium | Dave Rider | ||||
| 1994 | 9/2 | Science Hill | 10 | 0 | W | 1 | Home | Elizabethton | Brown Childress Stadium | Dave Rider | ||||
| 1995 | 8/25 | Science Hill | 28 | 29 | L | 1 | Away | Johnson City | Memorial Stadium | Dave Rider | ||||
| 1996 | 8/30 | Science Hill | 33 | 29 | W | 1 | Home | Elizabethton | Brown Childress Stadium | Dave Rider | ||||
| 1997 | 8/29 | Science Hill | 10 | 25 | L | 1 | Away | Johnson City | Memorial Stadium | Dave Rider | ||||
| 1998 | 8/28 | Science Hill | 49 | 12 | W | 1 | Home | Elizabethton | Brown Childress Stadium | Dave Rider | ||||
| 1999 | 8/27 | Science Hill | 56 | 20 | W | 1 | Away | Johnson City | Memorial Stadium | Dave Rider | ||||
| 2000 | 8/25 | Science Hill | 14 | 37 | L | 1 | Home | Elizabethton | Brown Childress Stadium | Tommy Jenkins | ||||
| 2001 | 8/24 | Science Hill | 14 | 35 | L | 1 | Away | Johnson City | Memorial Stadium | Tommy Jenkins | ||||
| 2002 | 8/30 | Science Hill | 34 | 28 | W | 1 | Home | Elizabethton | Brown Childress Stadium | Tommy Jenkins | ||||
| 2003 | 8/29 | Science Hill | 7 | 9 | L | 1 | Away | Johnson City | Memorial Stadium | Tommy Jenkins | ||||
| 2004 | 8/27 | Science Hill | 13 | 24 | L | 1 | Home | Elizabethton | Brown Childress Stadium | Eddie Pless | ||||
| 2005 | 8/26 | Science Hill | 6 | 12 | L | 1 | Away | Johnson City | Memorial Stadium | Eddie Pless | ||||
| 2006 | 8/25 | Science Hill | 7 | 21 | L | 1 | Home | Elizabethton | Brown Childress Stadium | Eddie Pless | ||||
| 2007 | 8/31 | Science Hill | 7 | 28 | L | 1 | Away | Johnson City | Memorial Stadium | Shawn Witten | ||||
| 2008 | 8/29 | Science Hill | 21 | 28 | L | 1 | Home | Elizabethton | Brown Childress Stadium | Shawn Witten | ||||
| 2009 | 8/28 | Science Hill | 23 | 14 | W | 1 | Away | Johnson City | Memorial Stadium | Shawn Witten | ||||
| 2010 | 8/27 | Science Hill | 7 | 14 | L | 1 | Home | Elizabethton | Brown Childress Stadium | Shawn Witten | ||||
| 2011 | 8/26 | Science Hill | 13 | 27 | L | 1 | Away | Johnson City | Kermit Tipton Stadium | Shawn Witten | ||||
| 2012 | 8/24 | Science Hill | 16 | 27 | L | 1 | Home | Elizabethton | Brown Childress Stadium | Shawn Witten | ||||
| 2013 | 8/30 | Science Hill | 35 | 40 | L | 1 | Away | Johnson City | Kermit Tipton Stadium | Shawn Witten | ||||
| 2014 | 8/29 | Science Hill | 34 | 56 | L | 1 | Home | Elizabethton | Brown Childress Stadium | Shawn Witten | ||||
| 2015 | 8/28 | Science Hill | 21 | 28 | L | 1 | Away | Johnson City | Kermit Tipton Stadium | Shawn Witten | ||||
| 2016 | 8/26 | Science Hill | 21 | 28 | L | 1 | Home | Elizabethton | Citizens Bank Stadium | Shawn Witten | ||||
| 2017 | 8/18 | Science Hill | 25 | 50 | L | 1 | Away | Johnson City | Kermit Tipton Stadium | Shawn Witten | ||||
| 2018 | 8/17 | Science Hill | 36 | 34 | W | 1 | Home | Elizabethton | Citizens Bank Stadium | Shawn Witten | ||||
| 2019 | 8/23 | Science Hill | 28 | 20 | W | 1 | Away | Johnson City | Kermit Tipton Stadium | Shawn Witten | ||||
| 2020 | 8/21 | Science Hill | 30 | 8 | W | 1 | Home | Elizabethton | Citizens Bank Stadium | Shawn Witten | ||||
| 2021 | 8/20 | Science Hill | 34 | 15 | W | 1 | Away | Johnson City | ETSU | Shawn Witten | ||||
| 2022 | 8/19 | Science Hill | 7 | 17 | L | 1 | Home | Elizabethton | Citizens Bank Stadium | Shawn Witten | ||||
| 2023 | 8/18 | Science Hill | 28 | 7 | W | 1 | Away | Johnson City | Kermit Tipton Stadium | Shawn Witten | ||||
| 2024 | 8/23 | Science Hill | 14 | 35 | L | 1 | Home | Elizabethton | Citizens Bank Stadium | Shawn Witten | ||||
| 2025 | 8/22 | Science Hill | 20 | 27 | L | 1 | Away | Johnson City | Kermit Tipton Stadium | Shawn Witten | ||||
| 2026 | 8/21 | Science Hill | 20 | 34 | L | 1 | Home | Elizabethton | Citizens Bank Stadium | Shawn Witten | ||||
| 1,579 | 1,843 | 38 | 59 | 5 | .397 | |||||||||
| 15.48 | 18.07 | -2.59 |