| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes | |
| 2000 | 8/19 | St. Xavier | 3 | 56 | L | 1 | Neutral | Lexington | Lexington Catholic High School | Paul Raines | |||||
| 2021 | 11/26 | St. Xavier | 21 | 31 | L | 1 | Away | Louisville | Mike Holcomb | playoff at Louisville | |||||
| 2025 | 10/30 | St. Xavier | 6 | 42 | L | 1 | Away | Louisville | William Blair | ||||||
| 30 | 129 | 0 | 3 | 0 | .000 | ||||||||||
| 10.00 | 43.00 | -33.00 |