| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes | |
| 1959 | 10/9 | Wheeling Central Catholic, WV | 22 | 8 | W | 1 | Home | Wellsville | Nicholson Stadium | Ken Woods | |||||
| 1960 | 10/7 | Wheeling Central Catholic, WV | 48 | 20 | W | 1 | Home | Wellsville | Nicholson Stadium | Ken Woods | |||||
| 1976 | 11/5 | Wheeling Central Catholic, WV | 12 | 6 | W | 1 | Home | Wellsville | Nicholson Stadium | Howard Gilger | |||||
| 1977 | 11/4 | Wheeling Central Catholic, WV | 0 | 32 | L | 1 | Away | Wheeling | Wheeling Island Stadium | Howard Gilger | |||||
| 1978 | 11/4 | Wheeling Central Catholic, WV | 3 | 0 | W | 1 | Home | Wellsville | Nicholson Stadium | Howard Gilger | |||||
| 1979 | 11/1 | Wheeling Central Catholic, WV | 7 | 17 | L | 1 | Away | Wheeling | Wheeling Island Stadium | Howard Gilger | |||||
| 1989 | 10/27 | Wheeling Central Catholic, WV | 8 | 48 | L | 1 | Away | Wheeling | Wheeling Island Stadium | Mike McVay | |||||
| 1990 | 10/26 | Wheeling Central Catholic, WV | 6 | 27 | L | 1 | Home | Wellsville | Nicholson Stadium | Bob Rudder | |||||
| 1992 | 11/5 | Wheeling Central Catholic, WV | 12 | 21 | L | 1 | Away | Wheeling | Wheeling Island Stadium | Robert Thayer | |||||
| 1993 | 11/5 | Wheeling Central Catholic, WV | 21 | 28 | L | 1 | Home | Wellsville | Nicholson Stadium | Robert Thayer | |||||
| 1994 | 11/5 | Wheeling Central Catholic, WV | 22 | 7 | W | 1 | Away | Wheeling | Wheeling Island Stadium | Robert Thayer | |||||
| 1995 | 11/3 | Wheeling Central Catholic, WV | 15 | 7 | W | 1 | Home | Wellsville | Nicholson Stadium | Eric Meek | |||||
| 1996 | 11/2 | Wheeling Central Catholic, WV | 0 | 30 | L | 1 | Away | Wheeling | Wheeling Island Stadium | Eric Meek | |||||
| 1997 | 10/17 | Wheeling Central Catholic, WV | 40 | 39 | W | 1 | Home | Wellsville | Nicholson Stadium | Eric Meek | |||||
| 1998 | 10/9 | Wheeling Central Catholic, WV | 13 | 10 | W | 1 | Away | Wheeling | Wheeling Island Stadium | Eric Meek | |||||
| 1999 | 9/24 | Wheeling Central Catholic, WV | 14 | 16 | L | 1 | Home | Wellsville | Nicholson Stadium | Eric Meek | |||||
| 2000 | 9/23 | Wheeling Central Catholic, WV | 12 | 48 | L | 1 | Home | Wellsville | Nicholson Stadium | Eric Meek | |||||
| 2001 | 9/21 | Wheeling Central Catholic, WV | 7 | 21 | L | 1 | Home | Wellsville | Nicholson Stadium | Eric Meek | |||||
| 2002 | 9/21 | Wheeling Central Catholic, WV | 6 | 31 | L | 1 | Away | Wheeling | Wheeling Island Stadium | Eric Meek | |||||
| 2003 | 9/19 | Wheeling Central Catholic, WV | 0 | 52 | L | 1 | Home | Wellsville | Nicholson Stadium | Ron Paul | |||||
| 2004 | 9/24 | Wheeling Central Catholic, WV | 13 | 54 | L | 1 | Away | Wheeling | Wheeling Island Stadium | Ron Paul | |||||
| 281 | 522 | 8 | 13 | 0 | .381 | ||||||||||
| 13.38 | 24.86 | -11.48 | |||||||||||||