| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes | |
| 2018 | 9/7 | Louisville | 20 | 31 | L | 1 | Away | Louisville | Jon Wallace | ||||||
| 2019 | 9/14 | Louisville | 34 | 49 | L | 1 | Home | Green | Green Memorial Stadium | Mark Geis | postponed from 9-13 | ||||
| 2021 | 10/1 | Louisville | 49 | 34 | W | 1 | Home | Green | Green Memorial Stadium | Mark Geis | |||||
| 2022 | 9/30 | Louisville | 23 | 27 | L | 1 | Away | Louisville | Mark Geis | ||||||
| 2023 | 9/29 | Louisville | 42 | 7 | W | 1 | Home | Green | Green Memorial Stadium | Mark Geis | |||||
| 2024 | 10/11 | Louisville | 28 | 0 | W | 1 | Away | Louisville | Mark Geis | ||||||
| 2025 | 10/10 | Louisville | 27 | 14 | W | 1 | Home | Green | Green Memorial Stadium | Mark Geis | |||||
| 2026 | 10/9 | Louisville | Away | Louisville | Mark Geis | ||||||||||
| 223 | 162 | 4 | 3 | 0 | .571 | ||||||||||
| 31.86 | 23.14 | 8.71 | |||||||||||||