| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes | |
| 1988 | 9/2 | Louisville | 12 | 14 | L | 1 | Home | Dover | Crater Stadium | Jim Reichenbach | |||||
| 1989 | 8/25 | Louisville | 14 | 0 | W | 1 | Away | Louisville | Jeff Souers | ||||||
| 1990 | 10/5 | Louisville | 28 | 21 | W | 1 | Home | Dover | Crater Stadium | Jeff Souers | |||||
| 1991 | 10/11 | Louisville | 6 | 41 | L | 1 | Away | Louisville | Jeff Souers | ||||||
| 1992 | 10/16 | Louisville | 12 | 28 | L | 1 | Home | Dover | Crater Stadium | Jeff Souers | |||||
| 2020 | 8/27 | Louisville | 19 | 10 | W | 1 | Home | Dover | Crater Stadium | Dan Ifft | |||||
| 2026 | 9/4 | Louisville | Home | Dover | Crater Stadium | Matt Rees | |||||||||
| 91 | 114 | 3 | 3 | 0 | .500 | ||||||||||
| 15.17 | 19.00 | -3.83 | |||||||||||||