| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes | |
| 1959 | 10/16 | Toledo St. Francis DeSales | 0 | 52 | L | 1 | Away | Toledo | Pete Schmidt | ||||||
| 1962 | 10/26 | Toledo St. Francis DeSales | 22 | 0 | W | 1 | Home | Defiance | Central Field | Wally Hood | |||||
| 2000 | 11/3 | Toledo St. Francis DeSales | 14 | 13 | W | 1 | Home | Defiance | Fred J. Brown Stadium | Jerry Buti | playoff at Defiance | ||||
| 36 | 65 | 2 | 1 | 0 | .667 | ||||||||||
| 12.00 | 21.67 | 9.67 | |||||||||||||