| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes | ||
| 1932 | 10/27 | Louisville | 0 | 39 | L | 1 | Away | Louisville | ||||||||
| 1933 | 10/26 | Louisville | 6 | 6 | T | 1 | Home | Columbiana | Firestone Park | |||||||
| 1934 | 10/25 | Louisville | 7 | 0 | W | 1 | Home | Columbiana | Firestone Park | Jim Wiand | ||||||
| 1935 | 10/24 | Louisville | 6 | 6 | T | 1 | Away | Louisville | Jim Wiand | |||||||
| 1936 | 10/24 | Louisville | 0 | 0 | T | 1 | Home | Columbiana | Firestone Park | Jim Wiand | ||||||
| 1937 | 10/23 | Louisville | 6 | 0 | W | 1 | Away | Louisville | Jim Wiand | |||||||
| 1938 | 10/22 | Louisville | 6 | 21 | L | 1 | Home | Columbiana | Firestone Park | Alfred Beach | ||||||
| 1939 | 10/21 | Louisville | 21 | 7 | W | 1 | Home | Columbiana | Firestone Park | Alfred Beach | ||||||
| 1940 | 10/19 | Louisville | 0 | 14 | L | 1 | Away | Louisville | Alfred Beach | |||||||
| 1941 | 9/27 | Louisville | 0 | 73 | L | 1 | Home | Columbiana | Firestone Park | Robert Payne | ||||||
| 1942 | 9/26 | Louisville | 0 | 14 | L | 1 | Away | Louisville | Mearl Atkins | |||||||
| 1943 | 9/25 | Louisville | 6 | 19 | L | 1 | Home | Columbiana | Firestone Park | Mearl Atkins | ||||||
| 1944 | 9/23 | Louisville | 26 | 0 | W | 1 | Away | Louisville | John Cabas | |||||||
| 1945 | 9/22 | Louisville | 0 | 20 | L | 1 | Home | Columbiana | Firestone Park | John Cabas | ||||||
| 1946 | 9/20 | Louisville | 25 | 7 | W | 1 | Away | Louisville | John Cabas | |||||||
| 1947 | 9/19 | Louisville | 0 | 27 | L | 1 | Away | Columbiana | Firestone Park | Jack Cramb | ||||||
| 1948 | 9/24 | Louisville | 0 | 40 | L | 1 | Away | Louisville | Jack Cramb | |||||||
| 1949 | 9/23 | Louisville | 0 | 41 | L | 1 | Home | Columbiana | Firestone Park | James Hall | ||||||
| 1950 | 9/22 | Louisville | 0 | 57 | L | 1 | Away | Louisville | James Hall | |||||||
| 1957 | 11/15 | Louisville | 26 | 12 | W | 1 | Away | Louisville | George Fisher | |||||||
| 1958 | 11/14 | Louisville | 12 | 8 | W | 1 | Home | Columbiana | Firestone Park | George Fisher | ||||||
| 1959 | 11/20 | Louisville | 0 | 32 | L | 1 | Away | Louisville | George Fisher | |||||||
| 1960 | 11/18 | Louisville | 30 | 14 | W | 1 | Home | Columbiana | Firestone Park | George Fisher | ||||||
| 1961 | 10/27 | Louisville | 14 | 0 | W | 1 | Away | Louisville | George Fisher | |||||||
| 1962 | 10/26 | Louisville | 8 | 20 | L | 1 | Home | Columbiana | Firestone Park | George Fisher | ||||||
| 1963 | 10/25 | Louisville | 0 | 48 | L | 1 | Away | Louisville | George Fisher | |||||||
| 1964 | 10/30 | Louisville | 0 | 40 | L | 1 | Home | Columbiana | Firestone Park | Ray Bellisari | ||||||
| 1965 | 10/29 | Louisville | 6 | 42 | L | 1 | Away | Louisville | Ray Bellisari | |||||||
| 1966 | 10/28 | Louisville | 0 | 12 | L | 1 | Home | Columbiana | Firestone Park | Ray Bellisari | ||||||
| 205 | 619 | 9 | 17 | 3 | .362 | |||||||||||
| 7.07 | 21.34 | -14.28 | ||||||||||||||